ExoticRx · exoticrx.com/drugs/hydrocortisone-oral
Cortef
Identical to endogenous cortisol. Binds glucocorticoid and mineralocorticoid receptors, providing physiologic replacement in adrenal insufficiency.
Shortest-acting oral corticosteroid — may need 2-3 daily doses. Used for Addison's disease replacement. Both gluco- and mineralocorticoid effects.
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Free-tier preview — dog and cat dosing. Pro and Student unlock all 2 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1 mg/kg | q12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 0.5–1 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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