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Gonadorelin (GnRH) for Cattle

Gonadorelin (GnRH) is used in cattle for cystic ovarian disease, ovarian cysts, Ovsynch/timed AI, Ovulation induction. Routes documented in cattle: IM, IV. ExoticRx tracks Gonadorelin (GnRH) dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Factrel, Fertagyl, Cystorelin, OvaCyst

Dose rules — sign in to view

Cited dose rules for Gonadorelin (GnRH) in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label; Plumb's Veterinary Drug Handbook

Mechanism of action

Synthetic gonadotropin-releasing hormone (GnRH) that stimulates release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the anterior pituitary. Causes ovulation or luteinization of follicles.

Side effects & warnings

Used in timed AI protocols (Ovsynch, CoSynch) in cattle. No withdrawal period required. Response depends on stage of estrous cycle and presence of a dominant follicle.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Gonadorelin (GnRH) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.