Gamithromycin for Cattle
Gamithromycin is used in cattle for Bovine respiratory disease (BRD), Not recommended, Not typically used in cats. Routes documented in cattle: SC. ExoticRx tracks Gamithromycin dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.
Trade names: Zactran
Dose rules — sign in to view
Cited dose rules for Gamithromycin in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.
Mechanism of action
Semi-synthetic 15-membered azalide macrolide. Binds 50S ribosomal subunit, inhibiting protein synthesis. Excellent tissue concentration and long half-life.
Side effects & warnings
Primarily cattle/swine. Fatal in horses (colitis). Single injection provides 7+ day coverage. SC injection in neck. Not for companion animal use generally.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Gamithromycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.