Question 1

What is Fludrocortisone used for?

Accepted Answer

Fludrocortisone is indicated for: Hypoadrenocorticism (Addison's disease), Hypoadrenocorticism (rare in cats).

Question 2

What routes can Fludrocortisone be administered by?

Accepted Answer

Available routes: PO.

Question 3

Which species have cited Fludrocortisone dosing data?

Accepted Answer

Fludrocortisone dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Question 4

Is Fludrocortisone a controlled substance?

Accepted Answer

Fludrocortisone is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Fludrocortisone?

Accepted Answer

Monitor electrolytes (Na/K ratio). Dose escalation over time is common. May cause PU/PD, weight gain, hypertension. Used for hypoadrenocorticism (Addison's).

Question 6

What are the side effects of Fludrocortisone?

Accepted Answer

Monitor electrolytes (Na/K ratio). Dose escalation over time is common. May cause PU/PD, weight gain, hypertension. Used for hypoadrenocorticism (Addison's).

Question 7

How does Fludrocortisone work?

Accepted Answer

Synthetic corticosteroid with potent mineralocorticoid activity promoting sodium retention and potassium excretion at the distal tubule. Also has glucocorticoid activity.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	PO	0.01–0.02 mg/kg	q12-24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	PO	0.01–0.02 mg/kg	q12-24h	Weak	Plumb's Veterinary Drug Handbook, 9th Ed

Fludrocortisone

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Fludrocortisone dosing data (2 dose rules)

Evidence levels across 2 dose rules

Backed by a published primary source

Sample dosing (2 of 2 cited rules)

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