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Erythromycin for Cattle

Erythromycin is used in cattle for Prokinetic (GI motility enhancement), Respiratory infection, Rhodococcus equi in foals (with rifampin), Rhodococcus equi pneumonia (foals). Routes documented in cattle: PO, IM. ExoticRx tracks Erythromycin dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Erythro-100, Gallimycin

Dose rules — sign in to view

Cited dose rules for Erythromycin in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Plumb's Veterinary Drug Handbook; Plumb's Veterinary Drug Handbook, 9th Ed

Mechanism of action

Binds 50S ribosomal subunit, inhibiting translocation of peptidyl-tRNA, blocking bacterial protein synthesis.

Side effects & warnings

CONTRAINDICATED in rabbits and hindgut fermenters. Prokinetic at sub-antimicrobial doses. GI upset common. Hepatotoxicity reported. Strong CYP inhibitor.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Erythromycin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.