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Deslorelin

Suprelorin

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Sourced from primary literature. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Endocrine

Routes

SC

Indications

Adrenal cortical diseaseadrenal disease (ferrets)behavior modificationBenign prostatic hyperplasiaChemical castrationChemical sterilizationChronic egg-layingMammary tumour recurrence reductionOvarian cystsReproductive suppression

Mechanism of Action

Slow-release GnRH agonist implant. Continuous stimulation desensitizes GnRH receptors, suppressing LH and FSH release.

Side effects & warnings

Initial hormone flare for 2-4 weeks. Duration varies by species (6-18 months). May trigger ovulation in some species before suppression. Remove implant to reverse effect.

Species with Deslorelin dosing data (16 dose rules)

African Grey ParrotBearded DragonCat (Domestic)Dog (Domestic)FerretGuinea PigPet RatRabbit (Domestic)

Evidence levels across 16 dose rules

Moderate×8Strong×3Extrapolated×4Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 4 published primary sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · ExoticRx 2026 (ferret dosing guide); Schoemaker NJ et al, Vet Rec 2008
  • · ExoticRx 2026 (rat dosing guide)
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 16 cited rules)

Free-tier preview — dog and cat dosing. Pro and Student unlock all 8 species including reptiles, birds, pocket pets, livestock, and equine.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)SC0 mg/animalonceModeratePlumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)SC0 mg/animalonceStrongPlumb's Veterinary Drug Handbook, 9th Ed

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