Danofloxacin for Cattle
Danofloxacin is used in cattle for Bovine respiratory disease (BRD), Severe gram-negative bacterial infections. Routes documented in cattle: SC, IV. ExoticRx tracks Danofloxacin dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.
Trade names: Advocin, A180
Dose rules — sign in to view
Cited dose rules for Danofloxacin in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.
Mechanism of action
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal activity against gram-negative and some gram-positive organisms.
Side effects & warnings
Avoid in growing animals (cartilage damage risk). Not for use in lactating dairy cattle. Injection site reactions possible. Avoid concurrent use with cation-containing products.
Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Danofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.
Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.