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Danofloxacin (Livestock) for Cattle

Danofloxacin (Livestock) is used in cattle for Bovine respiratory disease. Routes documented in cattle: SC. ExoticRx tracks Danofloxacin (Livestock) dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Advocin, A180

Dose rules — sign in to view

Cited dose rules for Danofloxacin (Livestock) in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: FDA NADA Label

Mechanism of action

Fluoroquinolone with concentration-dependent bactericidal activity. Inhibits DNA gyrase and topoisomerase IV. Achieves high pulmonary concentrations.

Side effects & warnings

For cattle only (BRD treatment). SC injection in the neck only. Not for use in dairy cattle 20 months of age or older. Observe withdrawal period for slaughter.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Danofloxacin (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.