ExoticRx · exoticrx.com/drugs/cobalamin
Cyanocobalamin, Hydroxocobalamin
Essential cofactor for methionine synthase and methylmalonyl-CoA mutase. Required for DNA synthesis, erythropoiesis, and neurological function.
Commonly deficient in cats with GI disease (IBD, lymphoma, EPI). SC injection q1-4 weeks or daily high-dose oral. Very safe — water-soluble, excess excreted renally. Monitor serum levels.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Free-tier preview — dog and cat dosing. Pro and Student unlock all 5 species including reptiles, birds, pocket pets, livestock, and equine.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 250–1000 mcg per dog | q7 days x 6 weeks, then monthly | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | SC | 250 mcg per cat | q7 days x 6 weeks, then q14 days x 6 weeks, the... | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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