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Ceftiofur for Cattle

Ceftiofur is used in cattle for Bacterial infections, Bovine respiratory disease, chronic abscess, Resistant Gram-negative. Routes documented in cattle: IM, SC. ExoticRx tracks Ceftiofur dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Excenel, Excede, Naxcel

Dose rules — sign in to view

Cited dose rules for Ceftiofur in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Carpenter 6e; Carpenter's Exotic Animal Formulary, 6th Ed; FARAD Withdrawal Guidelines; …

Mechanism of action

Veterinary third-generation cephalosporin. Metabolized to desfuroylceftiofur which retains antimicrobial activity. Broad gram-negative coverage.

Side effects & warnings

Veterinary-labeled product. Excede formulation provides extended duration. Do not use in animals producing milk for human consumption during withdrawal.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Ceftiofur pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.