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Cefquinome (Livestock) for Cattle

Cefquinome (Livestock) is used in cattle for arthritis in piglets, Bacterial meningitis, Bovine mastitis (E. coli, Klebsiella), Bovine respiratory disease. Routes documented in cattle: IM, SC, Intramammary. ExoticRx tracks Cefquinome (Livestock) dosing for cattle from primary veterinary literature; sign in to view the full rule set. Verify against current literature before clinical use.

Trade names: Cobactan

Dose rules — sign in to view

Cited dose rules for Cefquinome (Livestock) in cattle are available with a free ExoticRx account. Each row carries the route, dose range, frequency, indication, evidence level, and primary-source citation.

Sources include: Merck Veterinary Manual

Mechanism of action

Fourth-generation cephalosporin with broad-spectrum activity including many beta-lactamase-producing organisms. Stable against AmpC and extended-spectrum beta-lactamases.

Side effects & warnings

For cattle and swine. Not approved in US (available in EU). Intramammary formulation for bovine mastitis. Concerns about ESBL resistance selection limit use in some jurisdictions.

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Why a species-specific page? Cefquinome (Livestock) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from primary literature; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.